Biomedical Engineering Courses

*For more information regarding course equivalencies please refer to the Course Equivalency section, under “How to Read a Course Description“, in the CoE Bulletin Website:

200 Level Courses

BIOMEDE 211. Circuits and Systems for Biomedical Engineering.
Prerequisite: MATH 216 or 256 or 286, and Physics 240 or 260. Minimum grade of a “C-” required for enforced prerequisites. (4 credits)
Students learn circuits and linear systems concepts necessary for analysis and design of biomedical systems. Theory is motivated by examples from biomedical engineering. Topics covered include electrical circuit fundamentals, operational amplifiers, frequency response, electrical transients, impulse response, transfer functions and convolution, all motivated by circuit and biomedical examples. Elements of continuous time domain-frequency domain analytical techniques are developed. CourseProfile (ATLAS)

BIOMEDE 221. Biophysical Chemistry and Thermodynamics
Advisory Prerequisite: BIOL 172 or AP Biology Credit.
Prerequisite: (CHEM 130 or 210) and (MATH 116 or 121 or156 or 186). Minimum grade of a “C-” for enforced prerequisites. (4 credits)
The physio-chemical concepts and processes relevant to life. The emphasis lies on the molecular level. Topics: Biomimetics; Energy and Driving Forces; Biochemical Equilibria; Aqueous Solutions; Molecular Self-Assembly; Bio-electrochemistry; Biopolymers; Molecular Recognition and Binding Equilibria in Biology. CourseProfile (ATLAS)

BIOMEDE 231. Introduction to Biomechanics
Prerequisite: (MATH 116 or 121 or 156 or 186) and (PHYSICS 140 or 160). Minimum grade of a “C-” for enforced prerequisites. (4 credits)
Provides students with an introduction to topics in biomechanics, including statics, dynamics, and deformable body mechanics, as they apply to biological tissues and systems. CourseProfile (ATLAS)

BIOMEDE 241. Statistics, Computation, and Data Analysis for Biomedical Engineers 
Advisory Prerequisite: Concurrent or prior enrollment in MATH 116, 156, or 186 is recommended.
Prerequisite: ENGR 101 or 151 or EECS 183 or EECS 180 or ROB 102. Minimum grade of a “C-” for enforced prerequisites. (4 credits)
Integrates the fundamentals of descriptive statistics, discrete and random distributions, hypothesis testing, regression, ANOVA and post-hoc tests with computation, data analysis and visualization to address real world biomedical problems. Engaged learning class sessions focus on applying statistical and computational methods to real data sets from biomedical engineering. CourseProfile (ATLAS)

BIOMEDE 280. Undergraduate Research
Prerequisite: Permission of instructor. (1-4 credits)
This course offers research experience to first- and second-year Engineering students in an area of mutual interest to the student and to a faculty member within the College of Engineering. For each hour of credit, it is expected that the student will work a minimum of three hours per week. The grade for the course will be based on a final project/report evaluated by the faculty sponsor and participation in other required UROP activities, including bimonthly research group meetings and submission of a journal chronicling the research experience. CourseProfile (ATLAS)

BIOMEDE 295. Biomedical Engineering Seminar
Prerequisite: none. (1 credit)
Current research will be presented by faculty in the BME department.  The goal is to help students decide if they want to pursue a B.S. in BME or choose a different undergraduate major department as part of the SGUS program leading to an M.S. in BME. CourseProfile (ATLAS)

300 Level Courses

BIOMEDE 311. Biomedical Signals and Systems
Prerequisite: BIOMEDE 211, EECS 215, or EECS 314. (4 credits)
Theory and practice of signals and systems in both continuous and discrete time domains with examples from biomedical signal processing and control. Continuous-time linear systems convolution, steady-state responses, Fourier and Laplace transforms, transfer functions, poles and zeros, stability, sampling, feedback. Discrete-time linear systems: Z transform, filters, Fourier transform, signal processing. CourseProfile (ATLAS)

BIOMEDE 321. Bioreaction Engineering and Design
Prerequisite: BIOMEDE 221. Minimum grade of a “C-” for enforced prerequisite. (3 credits)
This course introduces topics in enzyme kinetics, enzyme inhibition, biochemical pathway engineering, mass and energy balance, cell growth and differentiation, cell engineering, bioreactor design, and analysis of the human body, organs, tissues, and cells as bioreactors.  The application of bioreaction/bioreactor principles to tissue engineering is also discussed. CourseProfile (ATLAS)

BIOMEDE 331. Introduction to Biofluid Mechanics
Prerequisite: (BIOMEDE 231); AND (Math 215 & 216); OR (Math 285 & 286). Minimum grade of a “C-” required for enforced prerequisites. (4 credits)
Introduces the fundamentals of biofluid dynamics and continuum mechanics, and covers the application of these principles to variety of biological flows.  Fluid flow in physiology and biotechnology is investigated at a variety of scales, ranging from subcellular to whole body. CourseProfile (ATLAS)

BIOMEDE 332. Introduction to Biosolid Mechanics
Prerequisite: BIOMEDE 231 and Math 215, or Math 285, and Math 216 or Math 286. Minimum grade of a “C-” required for enforced prerequisites. (4 credits)
Advised Prerequisite:  MATH 217
This course covers the fundamentals of continuum mechanics and constitutive modeling relevant for biological tissues. Constitutive models covered include linear elasticity, nonlinear elasticity, viscoelasticity and poroelasticity. Structure-function relationships which link tissue morphology and physiology to tissue constitutive models will be covered for skeletal, cardiovascular, pulmonary, abdominal, skin, eye and nervous tissues. CourseProfile (ATLAS)

BIOMEDE 350. Introduction to Biomedical Engineering Design
Prerequisite: ENGR 100, and [MATH 216 or 256 or 286] and BIOMEDE 231, and BIOMEDE 241. Minimum grade of a “C-” for enforced prerequisites. Advisory Prerequisite: BIOMEDE 211 and 221 (4 credits)
Problem-based learning to introduce students to biomedical engineering design concepts, tools, and
methodologies. Students will work in small groups and use virtual design and computational tools to propose and
validate feasible solutions to real-world biomedical engineering problems with industrial and/or clinical relevance. CourseProfile (ATLAS)

400 Level Courses

BIOMEDE 410 (MATSCIE 410). Design and Applications of Biomaterials
Prerequisite: MATSCIE 220 or 250 or permission of instructor. (3 credits)
Biomaterials and their physiological interactions. Materials used in medicine/dentistry: metals, ceramics, polymers, composites, resorbable, smart, natural materials. Material response/degradation: mechanical breakdown, corrosion, dissolution, leaching, chemical degradation, wear. Host responses: foreign body reactions, inflammation, wound healing, carcinogenicity, immunogenicity, cytotoxicity, infection, local/systemic effects. CourseProfile (ATLAS)

BIOMEDE 417 (EECS 417). Electrical Biophysics
Prerequisite: BIOMEDE 211 or EECS 215 or EECS 314, senior level undergraduate and/or graduate students. Minimum grade of a “C” required for enforced prerequisites. (4 credits)
Electrical biophysics of nerve and muscle; electrical conduction in excitable tissue; quantitative models for nerve and muscle including the Hodgkin Huxley equations; biopotential mapping, cardiac electrophysiology and functional electrical stimulation; group projects. Lecture and recitation. CourseProfile (ATLAS)

BIOMEDE 418. Quantitative Cell Biology
Advisory Prerequisite: MATH 216 or 256 or 286 and PHYSICS 240.
Prerequisite: BIOMEDE 221. Minimum grade of a “C-” for enforced prerequisites. (3 credits)

This course introduces the fundamentals of cell structure and functioning. The goal is to provide a general background in cell biology, with emphasis placed on physical aspects that are of particular interest to engineers. CourseProfile (ATLAS)

BIOMEDE 419. Quantitative Physiology
Prerequisite: BIOMEDE 221. Minimum grade of a “C-” for enforced prerequisites. (4 credits)
Quantitative Physiology provides learning opportunities for senior undergraduate and graduate students to understand and develop competencies in a quantitative, research oriented, systems approach to physiology.  Systems examined include cellular; musculoskeletal; cardiovascular; respiratory; endocrine; gastrointestinal; and renal.  Mathematical models and engineering analyses are used to describe system performance where applicable. CourseProfile (ATLAS)

BIOMEDE 424. (MECHENG 424) Engineering Acoustics
Prerequisite: MATH 216 and Physics 240. (3 credits)
Vibrating systems; acoustic wave equation; plane and spherical waves in fluid media; reflection and transmission at interfaces; propagation in lossy media; radiation and reception of acoustic waves; pipes, cavities and waveguides; resonators and filters; noise; selected topics in physiological, environmental and architectural acoustics. CourseProfile (ATLAS)

BIOMEDE 430. Rehabilitation Engineering and Assistive Technology
Prerequisite: Previous or simultaneous registration in IOE 333 or instructor approval. (3 credits)
This is a lecture course which surveys the design and application of rehabilitation engineering and assistive technologies in a wide range of areas, including wheeled mobility, seating and positioning, environmental control, computer access, augmentative communication, sensory aids, as well as emerging technologies. CourseProfile (ATLAS)

BIOMEDE 442. Introduction to Biomedical Imaging 
Prerequisite: (ENGR 101 or 151) or (EECS 180 or 183 or 280). Minimum grade requirement of “C- or better”. (3 credits)
Is an introduction course on biomedical imaging for undergrad and MS students. The topics cover all major imaging modalities, such as ultrasound, MRI, optical imaging, X-ray, computed tomography (CT), and nuclear imaging. This course will include lectures and visits to imaging laboratories and the UM hospital. CourseProfile (ATLAS)

BIOMEDE 450. Biomedical Engineering Design
Advisory Prerequisite: senior standing. prerequisite: BIOMEDE 350 and 458 (4 credits)
Interdisciplinary groups carry out biomedical instrumentation design projects sponsored by Medical School, College of Engineering, and local industry.  Students are exposed to the entire design process: design problem definition, generation of a design specification, documentation, design review process, prototype fabrication, testing, and calibration. Students may receive credit for either 450 or 451, not both. CourseProfile (ATLAS)

BIOMEDE 451. Biomedical Engineering Design, Part I
Advisory Prerequisite: BIOMEDE 458
Prerequisite: BIOMEDE 350 and senior standing. Minimum grade of a “C-” for enforced prerequisites. (3 credits)

Two semester course – Interdisciplinary groups design-build-test biomedical instrumentation projects.  Projects are sponsored by Medical School and Engineering research labs, and local industry.  Students are exposed to the entire design process:  design, problem definition, generation of a design specification, documentation, design review process, prototype fabrication, testing, and calibration. CourseProfile (ATLAS)

BIOMEDE 452. Biomedical Engineering Design, Part II
Advisory Prerequisite: senior standing. Prerequisite: BIOMEDE 350, 451, and 458. (3 credits)
Two semester course — Interdisciplinary groups design-build-test biomedical instrumentation projects.  Projects are sponsored by Medical School and Engineering research labs, and local industry.  Students are exposed to the entire design process:  design Problem definition, generation of a design specification, documentation, design review process, prototype fabrication, testing, and calibration. CourseProfile (ATLAS)

BIOMEDE 456 (MECHENG 456). Modeling in Biosolid Mechanics
Prerequisite: [BIOMEDE 231 or MECHENG 211], and [BIOMEDE 332 or MECHENG 382] (3 credits)
Definition of biological tissue and orthopaedic device mechanics including elastic, viscoelastic and non-linear elastic behavior.  Emphasis on structure function relationships.  Overview of tissue adaptation and the interaction between tissue mechanics and physiology. CourseProfile (ATLAS)

BIOMEDE 458 (EECS 458). Biomedical Instrumentation and Design
Prerequisite: BIOMEDE 211 or (EECS 215 or 314) or graduate standing. (4 credits)
Students design and construct functioning biomedical instruments. Hardware includes instrumentation amplifiers and active filters constructed using operational amplifiers. Signal acquisition, processing analysis and display are performed. Project modules include measurement of respiratory volume and flow rates, biopotentials (electrocardiogram), and optical analysis of arterial blood oxygen saturation (pulse-oximetry). CourseProfile (ATLAS)

BIOMEDE 464 (MATH 464). Inverse Problems
Prerequisite: MATH 217, MATH 417, or MATH 419; and MATH 216, MATH 256, MATH 286, or MATH 316. (3 credits)
Mathematical concepts used in the solution of inverse problems and analysis of related forward operators is discussed. Topics include ill-posedness, singular-value decomposition, generalized inverses, and regularization. Inverse problems considered (e.g., tomography, inverse scattering, image restoration, inverse heat conduction) are problems in biomedical engineering with analogs throughout science and engineering. CourseProfile (ATLAS)

BIOMEDE 474. Introduction to Tissue Engineering
Prerequisite: BME 410, senior standing or permission of instructor. (3 credits)
This course focuses on understanding the principles of tissue engineering and regenerative medicine. Emphasis is on the components and design criteria of tissue engineering constructs. The course will cover multiple examples of engineering soft and hard tissue and application of new technologies in regenerative medicine. CourseProfile (ATLAS)

BIOMEDE 476 (MECHENG 476). Biofluid Mechanics
Prerequisite: BIOMEDE 331 or MECHENG 320. (4 credits)
This is an intermediate level fluid mechanics course which uses examples from biotechnology processes and physiologic applications, including the cardiovascular, respiratory, ocular, renal, musculo-skeletal and gastrointestinal systems. CourseProfile (ATLAS)

BIOMEDE 479. Biotransport
Prerequisite: MATH 216 OR Math 286 OR Math 396, AND BIOMEDE 331 (Min grade requirement of C- or above). (4 credits)
Fundamentals of mass transport as it relates to biomedical systems. Convection, diffusion, osmosis and conservation of momentum, mass and energy will be applied to cellular and organ level transport. Examples of diffusion combined with reaction will also be examined. CourseProfile (ATLAS)

BIOMEDE 481 (NERS 481). Engineering Principles of Radiation Imaging
Prerequisite: none. (2 credits)
Analytic description of radiation production, transport and detection in radiation imaging systems. Measurements methods for image quality and statistical performance of observers. Systems for radiographic and radioisotope imaging, including film/screen, storage phosphor, and electronic radiography, fluoroscopy, computed tomography, Anger camera and PET systems. Emphasis on impact of random process on observer detection. CourseProfile (ATLAS)

BIOMEDE 484 (NERS 484) (ENSCEN 484). Radiological Health Engineering Fundamentals
Prerequisite: NERS 312 or equivalent or permission of instructor. (4 credits)
Fundamental physics behind radiological health engineering and topics in quantitative radiation protection. Radiation quantities and measurement, regulations and enforcement, external and internal dose estimation, radiation biology, radioactive waste issues, radon gas, emergencies and wide variety of radiation sources from health physics perspective. CourseProfile (ATLAS)

BIOMEDE 487. Artificial Intelligence in Biomedical Engineering
Advisory Prerequisite: Linear Algebra and BIOMEDE 241.
Prerequisite: (Biology 172, or 174, or 195); AND (Math 116 or 121); AND (Engr 101 or 151 or EECS 183, or 180); (C- or better); or Graduate Standing. Minimum grade of a “C-” for enforced prerequisites. (3 credits)
Introduces AI tools and applies them to real-world biomedical problems. Will cover a wide range of AI and machine-learning tools, biomedical data sets and disease applications. The focus will be on practical applications of AI in BME with hands-on tutorials and a design project. CourseProfile (ATLAS)

BIOMEDE 490. Directed Research
(1-4 credits)
Provides an opportunity for undergraduate students to perform directed research devoted to BiomedE. CourseProfile (ATLAS)

BIOMEDE 495. Introduction to Bioengineering
Prerequisite: Permission of instructor; mandatory pass/fail. (1 credit)
Definition of scope, challenge, and requirements of the bioengineering field. Faculty members review engineering-life sciences interdisciplinary activities as currently pursued in the College of Engineering and Medical School. CourseProfile (ATLAS)

BIOMEDE 499. Special Topics
(1-4 credits)

Topics of special interest selected by faculty. Lecture, seminar or laboratory. CourseProfile (ATLAS)

500 Level Courses

BIOMEDE 500 (UC 500). Biomedical Engineering Seminar
Mandatory, satisfactory/unsatisfactory. (1 credit)
This seminar will feature various bioengineering-related speakers. CourseProfile (ATLAS)

BIOMEDE 503. Statistical Methods for Biomedical Engineering
Prerequisite: Graduate standing or permission of instructor. (3 credits)
This course will cover descriptive statistics, probability theory, distributions for discrete and continuous variables, hypothesis testing and analysis of variance, as well as more advanced topics. We will make connections with real problems from engineering, biology and medicine, and computational tools will be used for examples and assignments. CourseProfile (ATLAS)

BIOMEDE 504 (Microbiology 504). Cellular Biotechnology
Prerequisite: Graduate student standing or consent of the instructor. (3 credits)
Biotechnology is a rapidly evolving, multi-disciplinary field that impacts nearly every aspect of our daily lives from the food we eat to the medicine we take. This course covers basic scientific and engineering principles behind this growing field, along with entrepreneurial aspects of translating innovative biotechnological solutions into new products. CourseProfile (ATLAS)

BIOMEDE 506 (MECHENG 506). Computational Modeling of Biological Tissues
Prerequisite: none. (3 credits)
Biological tissues have multiple scales and can adapt to their physical environment. This course focuses on visualization and modeling of tissue physics and adaptation. Examples include electrical conductivity of heart muscle and mechanics of hard and soft tissues. Homogenization theory is used for multiple scale modeling. CourseProfile (ATLAS)

BIOMEDE 510. Medical Imaging Laboratory
Prerequisite: BIOMEDE 516 or permission of instructor. Minimum grade requirement: B. (3 credits)
Provides the student practical, hands-on experience with research grade, medical imaging systems including x-ray, magnetic resonance, nuclear medicine, and ultrasound. Participants rotate through each of the respective areas and learn about and perform experiments to support previous theoretical instruction. CourseProfile (ATLAS)

BIOMEDE 516 (EECS 516). Medical Imaging Systems 
Advisory Prerequisite: EECS 351. (3 credits) 
Principles of modern medical imaging systems. For each modality the basic physics is described, leading to a systems model of the imager. Fundamental similarities between the imaging equations of different modalities will be stressed. Modalities covered include radiography, x-ray computed tomography (CT), NMR imaging (MRI) and real-time ultrasound. CourseProfile (ATLAS)

BIOMEDE 517. Sensing & Machine Learning for Neural Interfaces
Advisory Prerequisite: (BIOMEDE 211 or EECS 215 or EECS 314); and (EECS 216); and (Math 216); and (ENGR 101 or EECS 183 or EECS 180). (3 credits) 
Focuses on techniques for understanding and interacting with the nervous system. Students first implement quantitative models of neurons followed by models of recording and stimulation. Next students apply machine learning techniques to extract information from large neural datasets. CourseProfile (ATLAS)

BIOMEDE 519 (Physiol 519). Bioengineering Physiology
Prerequisite: MCDB 310 or Biol Chem 415, 451, 515 or CHEM 351 or permission of instructor. (4 credits)
Quantitative description of the structure and function of mammalian systems, including the neuromuscular, cardiovascular, respiratory, renal and endocrine systems. Mathematical models are used to describe system performance where applicable. Lectures, laboratories and problem sessions. CourseProfile (ATLAS)

BIOMEDE 522. Biomembranes: Transport, Signaling and Disease
Prerequisite: MCDB 310 or Biol Chem 415, 451, 515, or CHEM 351 and BIOMEDE 221 and CHEM 210 or permission of instructor. (3 credits)
This course focuses on the biochemistry and biophysics of transport and signaling processes through biomembranes and on the relevance of these processes for disease and therapy. The course discusses topics including composition of biomembranes; fluidity and self-assembly of lipids; membrane proteins; membrane potential; signal transduction. CourseProfile (ATLAS)

BIOMEDE 523. Business of Biology: The New Frontiers of Genomic Medicine
Prerequisite: Graduate Standing. (3 credits)
Advances in life science research have enhanced our understanding of the human genome, human genetic variation, and the role that genes play in our everyday health, response to treatment and susceptibility to disease. This new frontier in genomic medicine ushers in both opportunity and peril for individuals, companies and societies. The objective in this interdisciplinary graduate course is to explore the intersections between science, technology, commerce and social policy as they come together to advance (and in some cases retard) progress toward more-personalized health care. The course is intended for graduate students in medicine, biomedical and  health-related science, public health, law, engineering, and business interested in the future of health care. Due to variation in student backgrounds coming into the course, efforts are made to establish a shared vocabulary and knowledge base across the disciplines. Interdisciplinary student teams are assigned to a group research project which is presented at the end of the course. CourseProfile (ATLAS)

BIOMEDE 525 (Microb 525). Cellular and Molecular Networks
Prerequisite: BIOL 105 or BIOL 112 and MATH 215. (3 credits)
This course is designed to equip the student with appropriate concepts and techniques for the quantitative analysis of the integrated behavior of complex biochemical systems. A general approach is developed from the basic postulates of enzyme catalysis and is illustrated with numerous specific examples, primarily from the microbial cell. CourseProfile (ATLAS)

BIOMEDE 527. Current Topics in Neuromodulation
Prerequisite: BIOMEDE 417 or Graduate status. Minimum grade requirement: C-. (3 credits)
We will review current findings in neuromodulation, focusing on important recent work and seminal results. Engineering considerations common to electrical implants will be discussed, such as electrode measurement and design, packaging and circuits, and modeling of electrical fields and neurons. CourseProfile (ATLAS)

BIOMEDE 530. Rehabilitation Engineering and Technology Lab I
Prerequisite: Previous or simultaneous registration in BIOMEDE 430. (1 credit)
This is a lab course which provides hands-on experience in the use of assistive technologies and in-depth consideration of rehabilitation engineering research and design of assistive technologies for a wide range of areas, including environmental control, computer access, augmentative communication, wheeled mobility, sensory aids and seating and positioning. CourseProfile (ATLAS)

BIOMEDE 533 (KINE 530). Neuromechanics
Prerequisite: Graduate standing. (3 credits)
This course focuses on interactions of the nervous and musculoskeletal systems during human and animal movement with a focus on basic biological and engineering principles.  Topics will include neuromechanical control of movement, neurorehabilitation, biorobotics, and computer simulations of neuromechanical systems. CourseProfile (ATLAS)

BIOMEDE 534 (IOE 534) (MFG 534). Occupational Biomechanics
Prerequisite: IOE 333 or IOE 334. (3 credits)
Anatomical and physiological concepts are introduced to understand and predict human motor capabilities, with particular emphasis on the evaluation and design of manual activities in various occupations. Quantitative models are developed to explain: (1) muscle strength performance; (2) cumulative and acute musculoskeletal injury; (3) physical fatigue; and (4) human motion control. CourseProfile (ATLAS)

BIOMEDE 537. Computational Tools for Genomic Technologies
Prerequisite: [BIOL 172 OR 195] AND [ ENGR 101 OR 151, OR EECS 183 OR180, OR ROB 102 ]. Minimum grade requirement: C-. (3 credits)
The dramatic reductions in cost and accessibility of next-generation sequencing technologies has facilitated new approaches to understand disease and cellular biology . Understanding how to read sequencing datasets is not only incredibly useful for researchers seeking to glean insights into their own experiments but also the capacity to generate data-driven hypotheses. Develop an understanding of foundational methods in bioinformatics. CourseProfile (ATLAS)

BIOMEDE 550. Ethics and Enterprise
Prerequisite: None. (1 credit)
Ethics, technology transfer and technology protection pertaining to BiomedE are studied. Ethics issues range from the proper research conduct to identifying and managing conflicts of interest. Technology transfer studies the process and its influences on relationships between academia and industry. CourseProfile (ATLAS)

BIOMEDE 551 (BIOINF 551) (CHEM 551) (BiolChem 551). Proteome Informatics
Prerequisite: Bio Chem and calculus. (3 credits)
Introduction to proteomics, mass spectrometry, peptide identification and protein inference, statistical methods and computational algorithms, post-translational modifications, genome annotation and alternative splicing, quantitative proteomics and differential protein expression analysis, protein-protein interaction networks and protein complexes, data mining and analysis of large-scale data sets, clinical applications, related technologies such a metabolomics and protein arrays, data integration and systems biology. CourseProfile (ATLAS)

BIOMEDE 552. Biomedical Optics
Prerequisite: MATH 216. (3 credits)
This course provides students with an understanding of current research in biomedical optics. Topics include: fundamental theoretical principles of tissue optics; computational approaches to light transport in tissues; optical instrumentation; an overview of applications in clinical optical diagnostics and laser-based therapy; an introduction to biomedical microscopy and applications in biophotonic technology. CourseProfile (ATLAS)

BIOMEDE 556. Molecular and Cellular Biomechanics
Prerequisite: Senior standing. (3 credits)
This course will focus on how biomechanical and biophysical properties of subcellular structures can be determined and interpreted to reveal the workings of biological nano-machines. CourseProfile (ATLAS)

BIOMEDE 561. Biological Micro-and Nanotechnology
Prerequisite: Biol 172 or 174, Intro Physics and Chemistry, graduate standing, or permission of instructor. (3 credits)
Many life processes occur at small size-scales. This course covers scaling laws, biological solutions to coping with or taking advantage of small size, micro- and nanofabrication techniques, biochemistry and biomedical applications (genomics, proteomics, cell biology, diagnostics, etc.). There is an emphasis on micro fluidics, surface science and non-traditional fabrication techniques. CourseProfile (ATLAS)

BIOMEDE 563. (CHE 563) (MATSCIE 563) Biomolecular Engineering of Interfaces
Prerequisite: Senior or graduate standing. (3 credits)
This class focuses on biomolecular engineering of surfaces and interfaces in contact with biological systems. Recent advances in the interfacial design of materials as well as methods that enable studying such systems will be highlighted. CourseProfile (ATLAS)

BIOMEDE 574. Cells in Their Environment
Prerequisite: Graduate standing or permission of instructor. (3 credits)
This course focuses on how mammalian cells interact with the complex 3D environment that surrounds them in tissues. The goal is to provide students with a thorough understanding of how cell function is controlled and how this knowledge can be applied to the prevention and treatment of disease. CourseProfile (ATLAS)

BIOMEDE 580 (NERS 580). Computation Projects in Radiation Imaging
Prerequisite: Preceded or accompanied by NERS 481. (1 credit)
Computational projects illustrate principles of radiation imaging from NERS 481 (BIOMEDE 481). Students will model the performance of radiation systems as a function of design variables. Results will be in the form of computer displayed images. Students will evaluate results using observer experiments. Series of weekly projects are integrated to describe the performance of imaging systems. CourseProfile (ATLAS)

BIOMEDE 582 (NERS 582). Medical Radiological Health Engineering
Prerequisite: NERS 484 (BIOMEDE 484) or graduate status. (3 credits)
This course covers the fundamental approaches to radiation protection in radiology, nuclear medicine, radiotherapy and research environments at medical facilities. Topics presented include health effects, radiation dosimetry and dose estimation, quality control of imaging equipment, regulations, licensing and health physics program design. CourseProfile (ATLAS)

BIOMEDE 584 (CHE 584) (Biomaterials 584). Advances in Tissue Engineering
Prerequisite: Permission of Instructor; Advisory Prerequisite:  Graduate standing. (3 credits)
Fundamental engineering and biological principles underlying field of tissue engineering are studied, along with specific examples and strategies to engineer specific tissues for clinical use (e.g., skin). Student design teams propose new approaches to tissue engineering challenges. CourseProfile (ATLAS)

BIOMEDE 588 (CHE 588). Global Quality Systems and Regulatory Innovation 
Advisory Prerequisite: Senior or graduate students enrolled in the CoE and health related professional schools. (2 credits)
This course is for scientists, engineers, and clinicians to understand and interpret various relevant global and regional quality systems for traditional and cutting edge global health technologies, solutions and their implementation. Speakers from academia, the FDA, and biomedical related industries will be invited to participate in teaching this course. CourseProfile (ATLAS)

BIOMEDE 590. Directed Research
(Credits to be arranged)
Provides opportunity for Biomedical Engineering students to participate in the work of laboratories devoted to living systems studies. CourseProfile (ATLAS)

BIOMEDE 591. Thesis
Prerequisite: 2 hrs of BiomedE 590; mandatory satisfactory/ unsatisfactory. (credit to be arranged)
To be elected by bioengineering students pursuing the master’s thesis option. May be taken more than once up to a total of 6 credit hours. Graded on a satisfactory/unsatisfactory basis only. CourseProfile (ATLAS)

BIOMEDE 594. Recent Advances in Polymer Therapeutics
Prerequisite: BIOMEDE 410, senior standing, or permission of instructor. (3 credits)
The course will review the basic principles of polymer science and controlled drug delivery. The course will discuss specific examples of biopolymer applications in protein, peptide, nucleic acids, vaccine delivery and the formulation of nanostructured devices and their application in targeted delivery of therapeutic and imaging agents. CourseProfile (ATLAS)

BIOMEDE 596 (ChE 596) (Pharm 596). Health Science and Engineering Seminar
Prerequisite: Graduate standing. I, II (1 credit)
This seminar will feature invited speakers from pharmaceutical, biomedical and other life sciences-related industries and academic institutions. CourseProfile (ATLAS)

BIOMEDE 598 (ChE 598). Global Quality Sytems and Regulatory Innovation
Prerequisite: Senior or graduate students enrolled in the CoE and health related professional schools (2 credits)
This course is for scientists, engineers, and clinicians to understand and interpret various relevant global and regional quality systems for traditional and cutting edge global health technologies, solutions and their implementation. Speakers from academia, the FDA, and biomedical related industries will be invited to participate in teaching this course. CourseProfile (ATLAS)

BIOMEDE 599. Special Topics I, II
(1-6 credits)
Topics of current interest selected by the faculty. Lecture, seminar or laboratory. CourseProfile (ATLAS)

600 Level Courses

BIOMEDE 616 (ChE 616). Analysis of Chemical Signaling
Prerequisite: MATH 216, Biol Chem 415, 451, 515. (3 credits)
Quantitative analysis of chemical signaling systems, including receptor/ligand binding and trafficking, signal transduction and second messenger production and cellular responses such as adhesion and migration. CourseProfile (ATLAS)

BIOMEDE 646 (MECHENG 646). Mechanics of Human Movement
Prerequisite: MECHENG 540 (AEROSP 540) or MECHENG 543 or equivalent. (3 credits)
Dynamics of muscle and tendon, models of muscle contraction. Kinematics and dynamics of the human body, methods for generating equations of motion. Mechanics of proprioceptors and other sensors. Analysis of human movement, including gait, running and balance. Computer simulations and discussion of experimental measurement techniques. CourseProfile (ATLAS)

900 Level Courses

BIOMEDE 990. Dissertation/Pre-Candidate
(1-8 credits); (1-4 credits)
Dissertation work by doctoral student not yet admitted to status as candidate. The defense of the dissertation, that is, the final oral examination, must be held under a full-term candidacy enrollment. CourseProfile (ATLAS)

BIOMEDE 995. Dissertation/Candidate
Prerequisite: Graduate School authorization for admission as a doctoral candidate. (8 credits); (4 credits)
Election for dissertation work by a doctoral student who has been admitted to candidate status. The defense of the dissertation, that is, the final oral examination, must be held under a full-term candidacy enrollment. CourseProfile (ATLAS)